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目的:评价干燥脱水法长期保存角膜片在板层治疗性角膜移植术中的效果。方法:保存角膜片选自我院眼库干燥保存符合临床标准、复水透明的完整角膜片,临床病例选自我院角膜病组1976年8月～1999年12月期间行板层治疗性角膜移植患者1267例,从手术前后视力比较、原发病灶控制、植片存活情况进行临床效果综合分析。结果:保存角膜片复水透明合格率为94.9%,临床治愈率:感染性角膜溃疡/穿孔88.8%,血管翳性全角膜白斑98.3%,化学及热烧伤(穿孔,睑球角粘连等)92.1%,圆锥角膜及急性圆锥角膜99.5%,角膜变性(边缘性及前基质层)99.0%,其他88.9%,平均总治愈率:93.5%。结论:1.对各种严重的角膜感染、药物治疗无法控制的病人,治疗性角膜移植术是唯一有效的方法。2.采用无水氯化钙——硅胶干燥脱水长期保存的供体角膜能为临床随时提供角膜材料,是一项简单易行、便于推广应用的成功率很高的保存方法。眼科学报2003;19:110-113。
OBJECTIVE: To evaluate the long-term preservation of corneal dehydration in the therapeutic effect of keratoplasty. Methods: The preserved corneal sheets were selected from the eye bank of our hospital, and the cornea sheets were preserved in accordance with the clinical standard and rehydrated. The clinical cases were selected from the cornea patients of our hospital from August 1976 to December 1999 1267 cases, from the preoperative and postoperative visual acuity, control of primary lesions, survival of the implant clinical analysis of the comprehensive effect. Results: The pass rate of reconstituted corneal rehydration was 94.9%. The clinical cure rates were as follows: infectious corneal ulcer / perforation 88.8%, vascularized total corneal leukoplakia 98.3%, chemical and thermal burn (perforation, eyelid adhesion, etc.) 92.1 %, Keratoconus and acute keratoconus 99.5%, corneal degeneration (marginal and anterior stroma) 99.0%, the other 88.9%, the average total cure rate: 93.5%. Conclusion: 1. For all kinds of serious corneal infections, drug treatment can not control patients, therapeutic keratoplasty is the only effective method. 2. The use of anhydrous calcium chloride - silica gel dehydration dehydration long-term preservation of the donor corneal corneal material can provide clinical at any time, is a simple and easy to promote the application of high success rate of preservation. Journal of Ophthalmology 2003; 19: 110-113.