论文部分内容阅读
目的 :探讨蝎毒制剂———速可平 (SV)对急性期消化性胃溃疡 (APU)的治疗效果。方法 :46例APU患者随机分组 ,治疗组 2 3例采用速可平内镜下喷洒溃疡面 ,对照组 2 3例单用洁维乐凝胶内镜下喷洒溃疡面。结果 :2组治疗后主症及胃粘膜结构积分均有明显改善 (P <0 .0 5 ) ;溃疡周边胃粘膜血流量治疗后均有显著的改善 (P <0 .0 5 ) ,且治疗组较对照组改善更明显 (P <0 .0 5 ) ;治疗组胃溃疡治疗显效率及总有效率分别为 5 6 .5 %和 91.5 % ,与对照组 2 6 .0 %和 6 9.5 %相比 ,差异有显著性 (P <0 .0 1或P <0 .0 5 )。结论 :SV能迅速改善APU患者的症状和体征 ,促进溃疡的愈合 ,能有效改善溃疡周边胃粘膜血流量 ,无明显的副作用
Objective: To investigate the effect of scorpion venom formulation (SV) on acute peptic ulcer (APU). Methods: Forty-six patients with APU were randomly divided into two groups. In the treatment group, 21 patients were treated with Shu Keping ulcerative endoscopically and 30 patients in the control group were treated with Jieweile gel endoscopy alone. Results: The main symptoms and gastric mucosal structure scores of two groups were significantly improved after treatment (P <0.05); gastric mucosal blood flow around the ulcer were significantly improved (P <0.05), and the treatment (P <0.05). The effective rate and total effective rate of gastric ulcer in treatment group were respectively 56.5% and 91.5%, which were significantly lower than those in control group (26.0% vs 65.5% Compared with the difference was significant (P <0.01 or P <0.05). Conclusion: SV can rapidly improve the symptoms and signs of patients with APU, promote the healing of ulcer, and can effectively improve gastric mucosal blood flow around the ulcer without obvious side effects