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糖尿病性多发性神经炎是一种慢性的四肢远端对称性损害的多发性神经病,它具有四肢远端(尤其是下肢)对称性感觉和/或运动损害,有时也伴植物神经功能障碍。全世界约有五千万人患糖尿病,其神经系统的损害率相当高。世界卫生组织(WHO)组织10个国家的神经病研究中心进行了糖尿病周围神经病国际协作研究(简称WHOPNTF)自1980-1985年试用神经节苷脂(gangliosides)对糖尿病性多发性神经病患者进行治疗。上海第一医学院神经病学研究所(简称为“上海组”)是该协作组的成员之一。兹将上海组的总结材料报道如下:
Diabetic polyneuritis is a chronic polyneuropathy that is damaged by distal symmetry of the extremities and has symmetrical sensory and / or motor impairments in the distal extremities (especially the lower extremities), sometimes with autonomic dysfunction. About 50 million people worldwide are afflicted with diabetes and their nervous system has a high rate of damage. The International Cooperative Study on Diabetic Peripheral Neuropathy (WHOPNTF) was conducted by the Neurology Research Center of 10 countries in the World Health Organization (WHO) for the treatment of patients with diabetic polyneuropathy from gangliosides in 1980-1985. Shanghai First Medical College Institute of Neurology (referred to as the “Shanghai group”) is one of the members of the collaborative group. The Shanghai group’s summary material is hereby reported as follows: