粘液性水肿患者的心脏方面改变,早在1918年首先由Zondek氏描述。1925年Fahr氏更进一步的加以说明。国内自1958年首先由刘氏报道。现据不完全统计,陆续发表的病例至今共约有23例。但本病并非少见。我们仅在近3～4年已诊断6例,由于起病隐匿,病程发展缓慢,症状缺乏特征性,加之心脏扩大,心电图有改变和甲低所致的高胆固醇血症等,往往 Cardiac changes in patients with myxedema, first described by Zondek in 1918. Fahr’s 1925 further elaborates. Domestic since 1958, first reported by Liu. According to incomplete statistics, a total of 23 cases have been published so far. But the disease is not uncommon. We have only 6 cases diagnosed in the past 3 ~ 4 years. Due to the insidious onset, the slow course of the disease, the lack of symptoms, the enlarged heart, the change of ECG and the hypercholesterolemia caused by hypothyroidism,