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β-胡萝卜素是最重要的膳食成分之一。它除了具有维生素A活性外,尚有增强免疫应答、抗氧化、光保护、抗癌和预防心血管疾病的作用。然而其在哺乳动物体内的吸收、代谢与组织分布情况尚不完全明了。本文综述了近几年关于β-胡萝卜素吸收与代谢的种属差异性,在小肠内的摄取、吸收与代谢情况,与维生素E的相互作用,转化为视黄醇的中心与偏心性裂解机制以及视黄酸对视黄醇代谢的调节作用等方面的研究进展。
Beta-carotene is one of the most important dietary ingredients. In addition to its vitamin A activity, it has the effect of enhancing immune response, antioxidation, photoprotection, anticancer and prevention of cardiovascular diseases. However, its absorption, metabolism and tissue distribution in mammals are not completely understood. This review summarizes the species differences in the absorption and metabolism of β-carotene in recent years, the uptake, absorption and metabolism in the small intestine, the interaction with vitamin E, and the conversion of retinol center and eccentric fragmentation mechanism As well as retinoic acid regulation of retinol metabolism and other aspects of research.