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目的研究颈动脉粥样硬化及血脂水平对脑梗死的临床意义。方法对180例脑梗死病人及70例健康体检者行颈动脉超声及血脂分析检查。根据颈动脉超声检测结果将不同程度的颈动脉粥样硬化脑梗死病人分成A、B、C三组,并对不同程度的颈动脉粥样硬化与脑梗死病人的NIHSS评分及总胆固醇(TC)、甘油三酯(TG)水平与不同程度的颈动脉粥样硬化作对比分析。结果脑梗死组的颈动脉粥样硬化程度均较健康对照组严重,但随颈动脉粥样硬化的加重,A、B、C三组脑梗死病人的NIHSS评分无明显差异;脑梗死组的血TC、TG水平均显著高于健康对照组,且随颈动脉粥样硬化的加重,TC、TG水平逐渐升高。结论不同程度的颈动脉粥样硬化与脑梗死发病有关,但不能预示脑梗死的病情;血TC、TG水平与颈动脉粥样硬化相关。
Objective To study the clinical significance of carotid atherosclerosis and serum lipids on cerebral infarction. Methods 180 patients with cerebral infarction and 70 healthy subjects underwent carotid ultrasound and lipids analysis. According to the results of carotid artery ultrasound, patients with different grades of carotid atherosclerosis were divided into three groups: A, B and C, and the NIHSS scores and total cholesterol (TC) of patients with different degrees of carotid atherosclerosis and cerebral infarction , Triglyceride (TG) levels and different degrees of carotid atherosclerosis for comparative analysis. Results The degree of carotid atherosclerosis in patients with cerebral infarction was more severe than that in healthy controls. However, with the aggravation of carotid atherosclerosis, there was no significant difference in the NIHSS scores among patients with cerebral infarction (A, B and C) TC, TG levels were significantly higher than the healthy control group, and with the aggravation of carotid atherosclerosis, TC, TG levels gradually increased. Conclusions Carotid atherosclerosis is related to the incidence of cerebral infarction to some extent, but not to the prognosis of cerebral infarction. The levels of TC and TG are correlated with carotid atherosclerosis.