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鬼臼乙叉甙(VP-16-213,4′脱甲基-表鬼臼毒素-β-D-亚乙基葡糖甙)是从美国盾叶鬼臼或鬼臼的根中提取的鬼臼毒素的半合成衍生物。很早以前就发现鬼臼脂具有抗有丝分裂的活性。目前,鬼臼乙叉甙已成为一种重要的抗肿瘤药物。鬼臼乙叉甙单一或作为主药可治疗很多恶性肿瘤,包括 SCLC、睾丸癌、卡波济氏肉瘤、急性非淋巴性白血病、尤因氏瘤、妊娠胚芽细胞瘤、何杰金氏病、大细胞淋巴瘤、蕈状肉芽肿、神经母细胞瘤和儿童横纹肌肉瘤。另
Etoposide (VP-16-213,4′-demethyl-epipodophyllotoxin-β-D-ethyleneglycoside) is a ghost extracted from the roots of the American shield leaf or ghost Semi-synthetic derivatives of scorpion toxin. It has long been discovered that Podophyllum has an anti-mitotic activity. At present, Ecstasy has become an important anti-tumor drug. Erythropoietin alone or as a main drug can treat many malignant tumors, including SCLC, testicular cancer, Kaposi’s sarcoma, acute non-lymphocytic leukemia, Ewing’s tumor, gestational blastoma, Hodgkin’s disease, Large cell lymphoma, granuloma, neuroblastoma, and rhabdomyosarcoma in children. another