论文部分内容阅读
目的 :评估中西医综合治疗妊娠肝内胆汁淤积症 (ICP)的效果。方法 :观察组 12 0例采用以熊去氧胆酸为主的综合治疗 ,对照组仅用能量合剂治疗 ,治疗一周后 ,观察肝功能、胆酸、瘙痒评分。两组病人在孕 3 2周后行NST检查 ,分娩后比较两组围生儿预后及产妇预后情况。结果 :观察组血清总胆红素 (TBIL)、直接胆红素 (DBIL)、血清总胆汁酸 (TBA)、硷性磷酸酶 (ALP)及搔痒评分明显下降 ,与对照组比较差异有显著性意义 (P <0 0 5 ) ,观察组产时缺氧发生率低 ,新生儿窒息发生率低 ,剖宫产率较低 (P<0 0 5 )。结论 :以熊去氧胆酸为主的中西医综合治疗ICP是非常有效的
Objective: To evaluate the effect of integrated traditional Chinese and western medicine on intrahepatic cholestasis of pregnancy (ICP). Methods: The observation group of 120 cases with ursodeoxycholic acid-based comprehensive treatment, the control group only with energy mixture treatment, after a week of treatment, observe the liver function, bile acid, itching score. Two groups of patients were enrolled in the NST examination after 32 weeks of gestation. The outcomes of perinatal and postpartum maternal prognosis were compared between the two groups after delivery. Results: The levels of total bilirubin (TBIL), direct bilirubin (DBIL), serum total bile acid (TBA), alkaline phosphatase (ALP) and itching in the observation group decreased significantly compared with the control group (P <0.05). The observed incidence of hypoxia during birth was low, the incidence of neonatal asphyxia was low, and the rate of cesarean section was lower (P <0.05). Conclusion: The comprehensive treatment of ICP with traditional Chinese medicine and western medicine based on ursodeoxycholic acid is very effective