定量吸入器或喷雾器均可用于止喘药气雾吸入疗法。定量吸入器似乎比喷雾器更有效,而且用药较省,但使用时需要患者手的动作与呼吸运动相协调,而婴儿、老年人或残疾人往往难于做到。 为了使药物能有效地被吸入下呼吸道,气雾装置所产生的气雾粒子直径应为1～5μm(大多数粒子直径为0.5～3.5μm),以保证粒子在下呼吸道内最大程度的惯性运动和重力性沉积。患者应缓慢呼吸(作深呼吸更好)以增加达到下呼吸道的气雾量,然后患者屏气约10秒,让粒子沉降。在哮喘急性严重发作时,由于患者吸气率增加,屏气时间缩短、以及手的动作同呼吸运动不相协调等原因,气雾不能充分地吸入下呼吸道。因此,必须增加雾 Metered dose inhalers or nebulizers are available for asthma inhalation therapy. Metered dose inhalers appear to be more effective than nebulizers and dispense less medication, but require the patient’s hand to be coordinated with respiratory activity when used, often infants, the elderly, or the handicapped. In order for the drug to be effectively inhaled into the lower respiratory tract, aerosol particles generated by the aerosol device should have a diameter of 1 to 5 μm (most of the particles have a diameter of 0.5 to 3.5 μm) to ensure maximum particle inertia in the lower respiratory tract and Gravity deposition. The patient should breathe slowly (take a deep breath better) to increase the amount of aerosol that reaches the lower airway, and then hold the patient for about 10 seconds to allow the particles to settle. In acute exacerbation of asthma, aerosols can not inhale into the lower respiratory tract adequately due to increased patient inspiration, shortened breath holding time, and uncoordinated hand movements with respiratory movements. Therefore, we must increase the fog