多虑平(Doxepine)为三环类抗抑郁药,临床主要用于忧郁症的治疗,其对实验性胃溃疡的防治作用,我们已作了初步观察。本文将对其作用机理进行探讨。材料和方法动物全部实验用大鼠均由六安卫校动物室提供。雌雄不拘,体重为150—170g,集中喂养一周后供实验用。药品多虑平片,上海黄河制药厂生产,批号850802—1B;毛果芸香碱,上海医药站分装,批号780201;消炎痛片,上海黄河 Doxepine is a tricyclic antidepressant drug. It is mainly used in the treatment of depression, and its preventive and therapeutic effects on experimental gastric ulcer have been initially observed. This article will discuss its mechanism of action. Materials and Methods Animals All experimental rats were provided by the Sixth Health School animal room. Male or female, weight 150-170g, concentrated feeding for experimental use a week later. Drugs doxifene tablets, produced by Shanghai Huanghe Pharmaceutical Factory, batch No. 850802-1B; pilocarpine, Shanghai Pharmaceutical Station, batch No. 780201; Xiaoyantong Tablets, Shanghai Yellow River