生命早期(一般指胎儿期、婴幼儿期、儿童期)是生长发育的关键时期,这一阶段正是机体各器官、组织、细胞分化形成和发育成熟时期。大量的人群流行病学资料调查、前瞻性临床研究和动物实验研究结果表明,生命早期所处环境的不良刺激不仅影响出生前和出生后的生长发育,而且会对成年后的健康和生活质量产生远期乃至终生影响。现就这方面的研究进展综述如下。 Early life (usually refers to the fetus, infancy and childhood) is a critical period of growth and development, this stage is the body’s organs, tissues, cells and the formation of mature differentiation and development period. A large number of population epidemiological data, prospective clinical studies and animal experiments show that the early life environment adverse stimulus not only affects the growth before and after birth and development, but also on adult health and quality of life Long-term and even life-long impact. Now on the research progress in this area are summarized below.