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本文报告了广东省连南、连山两少数民族县部分地区17～35岁育龄期妇女,实施吸附精制破伤风类毒素免疫,分为两针次和三针次两个组,免疫后一个月的血清学效果表明,两针免疫组观察的101人中,免后有保护水平抗体者99人,占98.0％,TAT的GMT为684IU/L;三针免疫组观察了47人,免后有保护水平抗体者46人,占97.9％,其TAT的GMT为2760IU/L。两组之间GMT有着非常显著差异,但鉴于两针组的血清抗体滴度仍然比临界保护水平高64.8倍,故作者认为:从实际出发,对育龄期妇女实施“破类”免疫,两针免疫是可行的。
This article reports the women of childbearing age from 17 to 35 in some areas in Liannan and Lianshan counties of Guangdong Province. They are immunized with adsorbed purified tetanus toxoid and divided into two groups: The serological results showed that among the 101 patients observed by the two-dose immunization group, 99 were protected level antibodies after immunization (98.0%), the GMT of TAT was 684 IU / L, and 47 were observed in the three-dose immunization group 46 people with level of protection antibody, accounting for 97.9%, the GMT of TAT was 2760IU / L. The two groups of GMT has a very significant difference, but given the two needle group serum antibody titer is still higher than the critical protection level of 64.8 times, so the author thinks: from a practical point of view, women of childbearing age to implement “broken class” immunity, two needles Immunization is feasible.