无精子症是男性不育症中较为严重的一种疾病,其发病率为1%,占男性不育的5%~20%~([1])。无精子症分为梗阻性无精子症(obstructive azoospermia,OA)和非梗阻性无精子症。OA是指患者睾丸有正常的生精功能,由于先天性因素以及感染、医源性损伤等后天因素导致输精管道梗阻,使精子无法进入精液中。目前绝育而施行输精管结扎术导致OA的患者有6%~10%因各种原因(再婚、子女夭折等) Azoospermia is a more serious male infertility disease, the incidence rate of 1%, accounting for 5% to 20% of male infertility ~ ([1]). Azoospermia is divided into obstructive azoospermia (obstructive azoospermia, OA) and non-obstructive azoospermia. OA refers to the testes in patients with normal function of spermatogenesis, due to congenital factors and infection, iatrogenic injury and other acquired factors lead to obstruction of the ductus, sperm can not enter the semen. Current sterilization and vasectomy lead to OA in patients with 6% to 10% for a variety of reasons (remarriage, childbirth, etc.)