本文研究了电化学预处理碳纤维的各种条件,如处理电压、处理时间、处理后稳定时间、溶液条件等对局部麻醉药普鲁卡因、利多卡因电化学行为的影响.找出的电化学预处理最佳条件是在2.0V进行1.5min阳极化处理并在缓冲液中保持10min.普鲁卡因在pH=4~5之间,利多卡因在pH=6~7之间有较低的峰电位.运用最佳条件,普鲁卡因和利多卡因在毛细管电泳上5min内可获得很好的分离和检测. In this paper, the electrochemical pretreatment of carbon fiber under various conditions, such as the treatment voltage, the treatment time, the stability of the treatment time, the solution conditions on the local anesthetic procaine, lidocaine electrochemical behavior. The optimal conditions for chemical pretreatment were anodization at 2.0 V for 1.5 min and retention in buffer for 10 min. Procaine was more effective at pH = 4-7 than at pH = 6-7 Low peak potential.Using the best conditions, procaine and lidocaine in capillary electrophoresis within 5min can be very good separation and detection.