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大剂量皮质激素吸入加口服补肾中药对30例激素依赖型哮喘患者进行撤减治疗,结果表明:完全撤减成功的占70%,部分撤减成功的占6.7%,临床症状改善的有16.7%,完全无效的仅占6.7%,治疗后肺功能显著改善与治疗前相比,P<0.05,治疗前平均血浆皮质醇基值为0.152±0.07μmol/L,治疗后升至0.216±0.067μmol/L,P<0.001;Synacthen试验0min、60min和120min时点上唾液皮质醇值比治疗前显著上升(P<0.001)。提示大剂量皮质激素吸入加口服补肾中药是撤减口服皮质激素的好方法。
High-dose corticosteroid inhalation plus oral Chinese medicine on 30 patients with hormone-dependent asthma withdrawal therapy, the results showed that: complete withdrawal of success accounted for 70% of the successful reduction of 6.7% of the total, clinical symptoms improved 16.7%, completely invalid only accounted for 6.7%, significantly improved lung function after treatment compared with before treatment, P <0.05, before treatment, the mean plasma cortisol value of 0.152 ± 0.07μmol / L, after treatment rose to 0.216 ± 0.067μmol / L, P <0.001; Synacthen test at 0min, 60min and 120min saliva cortisol values were significantly higher than before treatment (P <0.001). Tip high-dose corticosteroid inhalation plus oral Chinese medicine is a good way to reduce oral corticosteroids.