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作者对血治核糖核酸酶活性测定的某些实验条件进行了观察,并测定了癌症治疗前、后、其他疾病患者及正常人共202例的血清核糖核酸酶活性。正常人为0。20±0.05单位。47例癌症患者治疗前为0.42±0.14单位,阳性率为87.7％,治疗后的血清核糖核酸酶活性阴转。其他疾病组假阳性率为14.9％。此法操作简单,不需特殊仪器和试剂,重复性较好,适用于临床常规,可作为诊断癌症和疗效观察的生物化学指标之一。
The authors observed some of the experimental conditions for the determination of blood RNase activity and determined the serum RNase activity of 202 patients before and after cancer treatment, other disease patients and normal subjects. Normal people 0.20 ± 0.05 units. 47 cases of cancer patients before treatment was 0.42 ± 0.14 units, the positive rate was 87.7%, after treatment, the serum ribonuclease activity turned negative. Other disease group false positive rate was 14.9%. This method is simple, does not require special instruments and reagents, reproducible, suitable for clinical practice, can be used as a diagnosis of cancer and efficacy of biochemical indicators.