本试验选择了青兰、葛根、芦丁、毛冬青等经提取制得总黄酮,分别加入15%的氢氧化铝、碳酸钙、糊精、乳糖、淀粉等为填充剂制片,共制得20种片剂,以探讨不同填充剂对这些片剂释放速率的影响。采用循环仪法在人工胃液中测定药物的释放曲线,然后用Weibull分布函数进行拟合,并提取参量得m值(形状参量)、T_(63)(释药量达63%的时间)。同时进行拟合 The experiment selected Qinglan, Pueraria lobata, Mao Dongqing obtained by extraction of the total flavonoids were added 15% of aluminum hydroxide, calcium carbonate, dextrin, lactose, starch, etc. as a filler preparation, were obtained 20 tablets to investigate the effect of different fillers on the release rate of these tablets. The release curve of the drug was measured by the method of circulator in artificial gastric juice, and then fitted with Weibull distribution function. The m value (shape parameter) and T_ (63) were extracted from the gastric juice (63% of the time). Simultaneous fitting