近30年来,心肌梗塞病死率下降了50％以上,而心肌梗塞后心力衰竭病死率则呈上升趋势,因此心肌梗塞后心功能不全的防治,变得十分重要。参脉注射液(由人参、麦冬组成),有益气生津、固脱复脉的作用,是中药治疗“气血两虚”的传统药物,已普遍用于临床。部分临床病例观察,它对急、慢性心肌梗塞都有一定的治疗作用,但尚缺乏动物实验的依据。本实验旨在通过建立大鼠心肌梗塞慢性心功能不全模型,观察参脉注 In the past 30 years, the mortality rate of myocardial infarction has dropped by more than 50%, and the mortality rate of heart failure after myocardial infarction has been on the rise. Therefore, the prevention and treatment of cardiac insufficiency after myocardial infarction becomes very important. Shenmai Injection (composed of ginseng and Ophiopogon japonicus) is a traditional medicine for the treatment of “qi and blood deficiency” and has been widely used in clinical practice. In some clinical cases, it has a certain therapeutic effect on acute and chronic myocardial infarction, but there is still no evidence for animal experiments. The purpose of this experiment was to establish a rat model of chronic myocardial insufficiency with myocardial infarction and observe