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鼻咽癌(NPC)一直受到人们注意。NPC组织病理学的分类依然有争议,下一批世界卫生组织推荐书将提出三种类型——角化型鳞状细胞癌;非角化型鳞状细胞癌;和未分化癌——但是很多人认为基本上是同一种肿瘤类型的组织学上的变异。而通常则主要是去解决诸如:组织病理学与不同的危险人群、不同的年龄组,人体白细胞抗原系统(HLA)与EB病毒(基因组及血清学)之间的关系。NPC已成功地移植到先天性无胸腺小鼠身上,并转移到局部淋巴结。在狗的各种病株中可明显自发生长的类似NPC的肿瘤已有报道,证明动物造模可资利用。
Nasopharyngeal carcinoma (NPC) has been receiving attention. The histopathological classification of NPC remains controversial. The next batch of WHO recommendations will propose three types of keratinizing squamous cell carcinoma; non-keratinizing squamous cell carcinoma; and undifferentiated carcinoma—but many People think that it is basically a histological variation of the same tumor type. Usually, it is mainly to solve the problems such as: histopathology and different dangerous populations, different age groups, the relationship between human leukocyte antigen system (HLA) and EB virus (genome and serology). NPC has been successfully transplanted into congenital athymic mice and metastasized to regional lymph nodes. It has been reported that long NPC-like tumors can develop spontaneously in various strains of dogs, proving that animal models can be used.