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目的对促红细胞生成素(EPO)皮下注射对老年慢性心力衰竭并贫血患者心功能及血红蛋白的影响进行分析研究。方法随机选择2013年12月至2015年2月收治的老年慢性心力衰竭合并贫血患者120例,将其平均分为对照组和观察组,对照组患者实施抗心力衰竭治疗,观察组实施EPO治疗。对两组患者的心功能指标、血红蛋白水平等指标进行观察比较。结果本研究中,观察组患者心功能各项指标较治疗前均有显著改善,差异有统计学意义(P<0.05)。观察组患者治疗后的心功能各项指标与对照组治疗后比较差有统计学意义(P<0.05)。观察组患者血红蛋白水平与治疗前比较差异有统计学意义(P<0.05);其与对照组患者治疗后比较差异有统计学意义(P<0.05)。结论在老年慢性心力衰竭并贫血患者治疗的过程中,实施EPO皮下注射治疗,可以显著改善患者的心功能及血红蛋白指标,降低患者病死率,治疗效果显著,可以在临床治疗中推广应用。
Objective To analyze the effects of erythropoietin (EPO) subcutaneous injection on heart function and hemoglobin in elderly patients with chronic heart failure and anemia. Methods A total of 120 elderly patients with chronic heart failure and anemia who were admitted to our hospital from December 2013 to February 2015 were randomly divided into control group and observation group. Patients in control group were treated with anti-heart failure, while those in observation group were treated with EPO. On the two groups of patients with cardiac function indicators, hemoglobin levels and other indicators were observed and compared. Results In this study, the indexes of cardiac function in observation group were significantly improved compared with that before treatment, the difference was statistically significant (P <0.05). The indexes of cardiac function after treatment in the observation group were statistically different from those in the control group after treatment (P <0.05). The hemoglobin level in the observation group was significantly different from that before treatment (P <0.05), and there was significant difference between the observation group and the control group after treatment (P <0.05). Conclusion In the treatment of elderly patients with chronic heart failure and anemia, subcutaneous injection of EPO can significantly improve the patient’s cardiac function and hemoglobin index, reduce the mortality of patients with significant therapeutic effect, which can be widely used in clinical treatment.