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目的探讨血清睾酮(T)/促黄体生成素(LH)、促卵泡激素(FSH)及LH水平检测在诊断睾丸生精作用中的价值。方法 55例原发性不育检查患者作为不育组,根据患者精子密度多少将其分为少精组(32例)、特发性无精组(2例)、极度少精组(21例)。并选取同期体检的55例健康男性为对照组。对所有患者均进行T/LH、FSH、LH水平进行测试,比较患者的各项水平。结果不育组患者的FSH为(20.43±2.62)U/L,LH为(10.71±4.92)U/L,明显高于对照组的(4.31±0.57)U/L、(6.02±3.76)U/L(P<0.05);对照组的T/LH为(1.26±0.56),明显高于不育组的(0.67±0.43),差异有统计学意义(P<0.05)。特发性无精组患者的FSH和LH激素水平明显高于极度少精组和少精组,极度少精组高于少精组,差异具有统计学意义(P<0.05);少精组的T/LH激素水平明显高于极度少精组和特发性无精组,极度少精组高于特发性无精组,差异具有统计学意义(P<0.05)。结论 FSH、T/LH与LH水平在临床上对睾丸生精作用检测的过程中十分重要,能够帮助临床医生充分的了解不育症患者睾丸生精的作用,临床应用价值较高,已经成为衡量不孕症患者睾丸生精水平的重要指标。
Objective To investigate the value of serum testosterone (T) / luteinizing hormone (LH), follicle stimulating hormone (FSH) and LH levels in the diagnosis of testicular spermatogenesis. Methods Fifty-five patients with primary infertility as infertile patients were divided into two groups according to their sperm densities: oligozoospermia group (32 cases), idiopathic azoospermia group (2 cases), and oligozoospermia group (21 cases ). 55 healthy males from the same period were selected as the control group. All patients were T / LH, FSH, LH levels were tested to compare the various levels of patients. Results The FSH was (20.43 ± 2.62) U / L and (10.71 ± 4.92) U / L in the infertility group, which was significantly higher than that in the control group (4.31 ± 0.57 U / L, (6.02 ± 3.76) U / L (P <0.05). The T / LH of the control group was (1.26 ± 0.56), which was significantly higher than that of the infertile group (0.67 ± 0.43), the difference was statistically significant (P <0.05). The levels of FSH and LH in idiopathic azoospermia group were significantly higher than those in the oligozoospermia group and the oligozoospermia group, and those in the oligozoospermia group were higher than those in the oligozoospermia group (P <0.05) The level of T / LH was significantly higher than that in the patients with severe oligozoospermia and idiopathic azoospermia, and the patients with severe oligozoospermia were higher than those with idiopathic azoospermia. The difference was statistically significant (P <0.05). Conclusions FSH, T / LH and LH levels are clinically important in the detection of testicular spermatogenesis. They can help clinicians fully understand the role of testicular spermatogenesis in infertile patients and have high clinical value and have become a measure Infertility in patients with testicular spermatogenesis an important indicator of the level.