目的探讨在反流性食管炎治疗中埃索美拉唑联合莫沙必利的应用效果。方法将我院收治的71例反流性食管炎患者根据入院顺序进行编号并利用随机数表法分组,对照组(35例)患者予以单一埃索美拉唑治疗,观察组患者在此基础上联合莫沙必利治疗,观察两组患者的治疗效果,进行临床对照性分析。结果观察组总有效率、临床症状积分、不良反应发生率均明显优于对照组(P<0.05)。结论在反流性食管炎治疗中埃索美拉唑联合莫沙必利的应用效果确切,具有“疗效好、安全性高”等优势,值得推广。 Objective To investigate the effect of esomeprazole combined with mosapride in the treatment of reflux esophagitis. Methods A total of 71 patients with reflux esophagitis admitted to our hospital were enrolled according to the order of hospital admission and randomized to a random number table. Patients in the control group (35 patients) were treated with single esomeprazole. On the basis of this, Combination of mosapride treatment, the two groups observed the effect of treatment, clinical control analysis. Results The total effective rate, clinical symptom scores and adverse reaction rate in the observation group were significantly better than those in the control group (P <0.05). Conclusion The application of esomeprazole combined with mosapride in the treatment of reflux esophagitis is effective and has the advantages of good curative effect and high safety and is worth popularizing.