前言Ts 细胞的概念对免疫学和临床医学都已产生了巨大的影响。有些疾病,如超敏反应和自身免疫性疾病被认为是缺少Ts 造成的。而另一些疾病,如免疫缺陷则被认为是Ts 过多的结果。甚至免疫学的基本概念,如免疫耐受,“自己”和“非己”的区分也常被认为是由抑制细胞与自身反应性T 和B 细胞之间的精细平衡所调节。Ts 细胞的概念也明显地影响了免疫学家解释他们的发现。免疫反应低下一般认为是由Ts 造成的。回顾过去的15年里发生的一些 Introduction The concept of Ts cells has had a tremendous impact on both immunology and clinical medicine. Some diseases, such as hypersensitivity and autoimmune diseases, are thought to be caused by the absence of Ts. Other diseases, such as immune deficiency, are thought to be the result of excessive Ts. Even the basic concept of immunology, such as immune tolerance, the distinction between “self” and “non-self” is often considered to be regulated by the fine balance between inhibiting cells and autoreactive T and B cells. The concept of Ts cells also significantly affected immunologists to explain their findings. Low immune response is generally believed to be caused by Ts. Looking back at some of the past 15 years