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白细胞介素17是来源于活化T淋巴细胞的细胞因子.研究发现白细胞介素17能维持纤维母细胞对CD34~+造血祖细胞的支持作用,并能介导它们向中性粒细胞增殖分化.目前也认为IL-17是最新发现的T淋巴细胞来源的作用于造血系统的细胞因子.本文对IL-17的来源、结构和功能等方面作一综述.
Interleukin 17 is a cytokine derived from activated T lymphocytes, and it was found that interleukin 17 (IL-17) can support fibroblasts in supporting CD34 + hematopoietic progenitor cells and mediate their proliferation and differentiation into neutrophils. It is also thought that IL-17 is the newly discovered T lymphocyte-derived cytokine that acts on the hematopoietic system.In this paper, the origin, structure and function of IL-17 are reviewed.