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穿透性角膜移植是治疗角膜盲的主要手段,尽管角膜是器官移植的免疫赦免部位,但同种异体免疫排斥反应仍是角膜移植片失败的主要原因。据统计,18%的常规角膜移植或75%的高危角膜移植患者会发生排斥反应。目前临床使用的各种免疫抑制剂主要通过作用于T淋巴细胞达到抑制免
Penetrating keratoplasty is the main method of treating corneal blindness. Although the cornea is the immunoprecipitated site of organ transplantation, allogeneic immune rejection remains the main reason for the failure of corneal graft. According to statistics, rejection occurs in 18% of patients with conventional corneal transplantation or in 75% of patients with high-risk keratoplasty. The current clinical use of various immunosuppressive agents mainly through the role of inhibition in T lymphocytes to avoid