热休克蛋白是一类广泛存在的具有高度保守性的应激蛋白,有着重要的生理功能。结核病是一种慢性感染性疾病,近年来流行趋势逐渐加剧,严重危害人类的健康。越来越多的研究表明热休克蛋白参与了结核的发病过程,与结核分枝杆菌的致病性、免疫性和结核病的诊断及治疗等方面有着密切的联系。 Heat shock protein is a kind of widespread and highly conserved stress protein, which has important physiological functions. Tuberculosis is a chronic infectious disease, and its epidemic trend has been aggravating in recent years, seriously endangering human health. More and more researches have shown that heat shock protein is involved in the pathogenesis of tuberculosis and closely linked to the pathogenicity and immunogenicity of tuberculosis and the diagnosis and treatment of tuberculosis.