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目的 为了观察肝切除加置化疗泵对预防肝癌复发的效果。方法 试验组 4 3例在行肝切除的基础上加作肝动脉或 /和门静脉化疗泵植入 ,术后定期进行化疗栓塞 ,对照组单纯行肝切除 ,两组随访 1～ 4年。结果试验组 1、3年复发率 (分别为 14 % ,3 5 % )明显低于对照组 (分别为 4 2 % ,72 % ) (P <0 .0 1)。而术后生存率 1、3年试验组为 79%、67%明显高于对照组为 5 1%、3 2 % (P <0 .0 5 )。结论 肝切除加置化疗泵行肝动脉或 /和门静脉化疗栓塞是预防肝癌术后复发和提高远期疗效的有效措施。
Objective To observe the effect of hepatectomy and chemotherapy pump on the prevention of recurrence of liver cancer. Methods Forty-three patients in the experimental group were treated with hepatic artery or portal vein chemotherapy pump implantation on the basis of liver resection. Chemoembolization was performed on a regular basis after surgery. The control group underwent hepatectomy alone. The two groups were followed up for 1 to 4 years. Results The recurrence rates in the trial group at 1 and 3 years (14% and 35%, respectively) were significantly lower than those in the control group (42% and 72%, respectively) (P < 0.01). The postoperative survival rate was 79% in the experimental group at 3 years and 67% in the experimental group was significantly higher than that in the control group at 51% and 32% (P < 0.05). Conclusion Hepatectomy plus chemotherapy pump for hepatic artery or portal vein chemoembolization is an effective measure to prevent postoperative recurrence of liver cancer and improve long-term efficacy.