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目的:回顾性分析上颌窦癌放射治疗(部分结合手术治疗)远期疗效和预后因素。方法:对33例上颌窦癌采用单纯体外放射治疗或结合手术综合治疗,随访资料按Kgplan-Meier法统计生存率,Log-rank检验和Cox多因素回归分析探讨影响疗效的预后因素。结果:33例1、3、5年生存率分别是93%、65%和32%;放疗结合手术综合治疗的远期疗效较单纯放疗好(P<0.01);不同病理类型之间以及不同照射剂量之间生存期相差显著(P<0.01)。结论:上颌窦癌应尽可能采取手术结合放疗的综合治疗;病理类型和治疗方式是影响预后的主要因素,性别、年龄和发生部位对预后无明显影响。
Objective: To retrospectively analyze the long-term efficacy and prognostic factors of maxillary sinus cancer treated by radiotherapy (partially combined with surgical treatment). Methods: Thirty-three patients with maxillary sinus cancer were treated with external beam radiotherapy alone or combined with surgery. The follow-up data were analyzed by Kgplan-Meier statistical survival rate, Log-rank test and Cox regression analysis to evaluate the prognostic factors. Results: The 1, 3, 5-year survival rates of 33 patients were 93%, 65% and 32% respectively. The long-term curative effect of combined radiotherapy and radiotherapy was better than radiotherapy alone (P <0.01) The difference in survival between different irradiation doses was significant (P <0.01). Conclusion: The treatment of maxillary sinus cancer should be combined with surgery and radiotherapy as far as possible. The pathological types and treatment methods are the main factors affecting the prognosis. Sex, age and site of occurrence have no significant effect on the prognosis.