论文部分内容阅读
目的 观察苯甲酸雌二醇对腹腔镜下腹膜阴道成形术后阴道上皮的影响。方法 将2003年1月至2011年3月在邢台市人民医院行腹腔镜腹膜阴道成形术的40例患者随机分成实验组与对照组,每组各20例。实验组于人工成形的阴道内涂抹苯甲酸雌二醇软膏,每日1.5g,连用3个月;对照组不用任何雌激素类药物。结果 术后3个月阴道长度实验组为(9.1±0.4)cm,对照组为(9.0±0.6)cm,两组比较差异无统计学意义(P>0.05);但实验组阴道弹性好,并发症发生率低。实验组术后3个月阴道涂片结果为:可见大量复层鳞状上皮细胞,少量炎症细胞,阴道细胞成熟指数[Vaginalexfoliatecellmaturationindex,MI(%)]为(50.2±10.5)。对照组为:可见中等炎症细胞,少许鳞状上皮细胞。结论 苯甲酸雌二醇应用于腹腔镜腹膜阴道成形术后可增加阴道上皮弹性,促进人工阴道鳞状上皮化,减少并发症。
Objective To observe the effect of estradiol benzoate on vaginal epithelium after laparoscopic peritoneal vaginoplasty. Methods From January 2003 to March 2011, 40 patients undergoing laparoscopic peritoneal vaginoplasty in Xingtai People’s Hospital were randomly divided into experimental group and control group, with 20 cases in each group. The experimental group in the artificial vaginal coating oestradiol benzoate ointment, 1.5g daily, once every 3 months; the control group without any estrogen drugs. Results The vaginal length at 3 months postoperatively was (9.1 ± 0.4) cm in the experimental group and (9.0 ± 0.6) cm in the control group, but there was no significant difference between the two groups (P> 0.05). However, the vaginal elasticity of the experimental group was good Low incidence of disease. The result of vaginal smear 3 months after operation in the experimental group was: a large number of stratified squamous epithelial cells and a few inflammatory cells were observed. The vaginal cell maturation index [Vaginalexfoliatecellmaturationindex, MI (%)] was (50.2 ± 10.5). Control group: visible medium inflammatory cells, a small amount of squamous epithelial cells. Conclusion Estradiol benzoate used in laparoscopic peritoneal vaginoplasty can increase vaginal epithelial elasticity, promote artificial vaginal squamous epithelium, reduce complications.