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目的观察宫腔内置入米索前列醇联合缩宫素用于预防妊高征剖宫产产后出血的临床效果。方法选取医院妇产科进行剖宫产的妊高征产妇112例作为研究对象,随机分为对照组和观察组,每组56例。对照组给予宫体单纯注射缩宫素治疗,观察组在对照组基础上给予米索前列醇进行宫腔内置入,观察2组产妇术后阴道出血量及不良反应发生情况。结果观察组术后2 h、24 h及总出血量均少于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率为5.36%,低于对照组的14.29%(P<0.05)。结论宫腔内置入米索前列醇联合缩宫素用于预防妊高征剖宫产产后出血的疗效确切,可对阴道出血起着预防作用,且不良反应少,值得临床推广应用。
Objective To observe the clinical effect of intrauterine misoprostol combined with oxytocin in the prevention of postpartum hemorrhage due to pregnancy-induced hypertension. Methods A total of 112 pregnant women with PIH who underwent cesarean section were randomly divided into control group and observation group, 56 cases in each group. The control group was treated with oxytocin injection. The observation group was given intrauterine implantation of misoprostol on the basis of the control group. The incidence of vaginal bleeding and adverse reactions in the two groups were observed. Results The observation group at 2 h, 24 h and total bleeding were less than the control group, the difference was statistically significant (P <0.05). The incidence of adverse reactions in the observation group was 5.36%, which was lower than 14.29% in the control group (P <0.05). Conclusion Intra-uterine insertion of misoprostol combined with oxytocin is effective in preventing bleeding after cesarean section in pregnancy-induced hypertension. It can prevent vaginal bleeding and has fewer adverse reactions. It is worthy of clinical application.