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急性单核细胞白血病(AMoL)根据形态可分M5a、M5b两型。Berger等(1980、19目年)发现AMoL染色体的11q重排发生率很高,且常为M5a。第四次白血病染色体国际会议(1984年)指出:22%AMoL病人11q异常,主要与M5a有关。在文献中,仅有2份报道指出恶性疾病的获得性染色体重排与t(8;16)(p11;p13)有关。从Schouten(1982年)、Bernstein(1984年)各报道的1例和近期报道3例中,5例似乎都是AMoL。髓片中除有一些典型的幼维细胞外,另一些则为分化很好的细胞。作者对其中2例骨髓涂片复查,发现其形态很有特点:都有吞噬红细胞现象;这细胞分别占全髓片有核细胞数的1.8%和2.0%。这一发现与Schouten利
Acute monocytic leukemia (AMoL) according to the morphology can be divided into M5a, M5b two types. Berger et al. (1980, 19) found a high incidence of 11q rearrangements in AMoL chromosomes, often M5a. The Fourth International Conference on Leukemia Chromosomes (1984) states that 11q abnormalities occur in 22% of AMoL patients and are mainly associated with M5a. In the literature, only two reports indicate that acquired chromosomal rearrangements in malignant disease are associated with t (8; 16) (p11; p13). From Schouten (1982), Bernstein (1984) reported in 1 case and 3 recently reported cases, 5 cases appear to be AMoL. In addition to some of the typical parenchymal cells in the marrow, while others are well differentiated cells. The author of which 2 cases of bone marrow smear review and found that its morphology is very characteristic: all have phagocytosed erythrocyte phenomenon; this cell accounted for 1.8% and 2.0% of the total number of nucleated cells nucleated cells. This discovery and Schouten Lee