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目的 观察灯盏细辛注射液治疗脑梗死的临床疗效及副作用。方法 随机分为治疗组 42例 ,对照组 40例。治疗组采用云南灯盏细辛注射液 3 0ml加入生理盐水 2 5 0ml中静滴 ,对照组采用复方丹参注射液 2 0ml加入生理盐水 2 5 0ml中静滴 ,均每日 1次 ,疗程 10～ 2 0天。结果 两组治疗前后神经功能缺损程度评分比较 :治疗组优于对照组 ,两组比较有非常显著差异 (P <0 .0 0 1)。治疗组显效率 70 .0 % ,对照组为 48.6% ,两组比较有显著差异 (P <0 .0 1)。治疗组治疗后血脂明显下降 ,治疗前后血脂比较有显著差异 (P <0 .0 1,P <0 .0 5 )。两组治疗过程中未发现明显毒副作用 ,治疗组中 2例出现胸闷、头胀 ,1例出现四肢关节疼痛、低热 ,经对症处理后消失。两组血、尿常规、肝肾功能化验无异常。结论 灯盏细辛注射液治疗脑梗死疗效好、副作用小 ,安全可靠 ,值得临床推广应用
Objective To observe the clinical efficacy and side effects of Dengzhanxixin injection in treating cerebral infarction. Methods were randomly divided into treatment group 42 cases, control group 40 cases. In the treatment group, Yunnan Erigeronum Injection 30ml was added to 250ml of normal saline intravenously, while in the control group 20ml of compound Danshen injection was added to 250ml of normal saline intravenously once a day for 10 ~ 2 0 days. Results The score of neurological deficits in both groups before and after treatment was significantly higher in the treatment group than in the control group, with significant difference between the two groups (P <0.01). The effective rate was 70.0% in the treatment group and 48.6% in the control group, with significant difference between the two groups (P <0.01). After treatment, the blood lipids in the treatment group decreased significantly, and there was significant difference in the blood lipid between before and after treatment (P <0.01, P <0.05). No significant side effects were found during the two groups. Two cases in the treatment group had chest tightness and swollen head, one case had joint pain and fever in four limbs, and disappeared after symptomatic treatment. Two groups of blood, urine, liver and kidney function tests were normal. Conclusion Erigeron injection is effective in treating cerebral infarction with small side effects, safe and reliable, and worthy of clinical application