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晚期HD 及高度恶性NHL一线化疗后复发进行二线化疗通常复发早、对化疗反应差、长期生存率低。而单用放疗作为这类病人的补救措施往往很少被采用。根据已发表的为数不多的研究结果看,放疗对复发性HD 或NHL 的治疗常常是有效的,作者报道了8例病人的治疗结果。6例HD 及2例高度恶性NHL,病理或临床分期为ⅠA～ⅣB.6例最初单用化疗,2例同时使用外野放疗,结果8例均复发(但放射区病灶再无复发),复发病灶均为结节性,1例伴有局眼性骨累犯。除1例病人使用铯137单位放疗外,其余7例采用8Mev的线性加速器治疗。肿瘤剂量为2000～4500cgy,治疗时间1～12周。放疗前1例病人行睥切除术,另1例行脾切除加部分肠及胰尾切除。
Second-line chemotherapy is usually relapsed early after first-line chemotherapy for advanced HD and highly-malignant NHL, and has poor response to chemotherapy and low long-term survival. Remedies for radiotherapy alone are rarely used. According to the few studies published, radiotherapy is often effective in the treatment of recurrent HD or NHL, and the authors reported the results of treatment in 8 patients. 6 cases of HD and 2 cases of high grade NHL. The pathological or clinical stage was ⅠA-ⅣB. The first chemotherapy alone was performed in 6 cases and the outfield radiotherapy was used in 2 cases. All 8 cases had recurrence (no recurrence in the radiation area) All were nodular, 1 with ocular bone recidivism. Except for 1 patient using cesium-137 unit radiotherapy, the remaining 7 patients were treated with a 8 Mev linear accelerator. Tumor dose of 2000 ~ 4500cgy, treatment time of 1 to 12 weeks. One patient underwent radiotherapy before hysterotomy, and the other one underwent splenectomy plus partial intestine and pancreatic tail resection.