中草药已在中国药典中使用了数千年。木兰属的厚朴,主要用于治疗焦虑、哮喘、抑郁症、胃肠道疾病、头痛。其树皮提取物是目前市售的食品补充剂和化妆品的主要成分。厚朴及其主要成分具有多种药理活性,具有抗氧化、抗炎、抗生素和抗痉挛作用。然而,相关机制尚未明确,临床试验也鲜有报道。体外和体内毒性研究已经发现了一些有趣的特征。本文旨在总结关于厚朴的成分、利用、药理学和安全性的文献。 Chinese herbal medicine has been used in Chinese Pharmacopoeia for thousands of years. Magnolia Magnolia, mainly for the treatment of anxiety, asthma, depression, gastrointestinal diseases, headache. Its bark extract is currently the main ingredient of food supplements and cosmetics. Magnolia officinalis and its main components have a variety of pharmacological activities, with anti-oxidation, anti-inflammatory, antibiotics and anti-spasticity. However, the relevant mechanisms are not yet clear, and few clinical trials have been reported. In vitro and in vivo toxicity studies have found some interesting features. This article aims to summarize the literature on the composition, utilization, pharmacology and safety of Magnolia officinalis.