肥厚型心肌病扩张期是肥厚型心肌病的终末期改变,病理特征为心腔整体的扩大、室壁的弥漫性纤维化及小动脉管腔闭塞。肥厚型心肌病扩张期的发生与遗传因素、微循环障碍、炎症反应、氧化应激及酒精等多种因素密切相关。尽管肥厚型心肌病扩张期发病率较低,但是往往症状严重,一般药物治疗疗效不佳,通常需要心脏移植。 Hypertrophic cardiomyopathy is the expansion of hypertrophic cardiomyopathy end-stage changes in the pathological features of the expansion of the entire heart chamber, parietal diffuse fibrosis and arteriole occlusion. Hypertrophic cardiomyopathy occurs with the expansion of genetic factors, microcirculation, inflammation, oxidative stress and alcohol and other factors are closely related. Although the low incidence of hypertrophic cardiomyopathy dilatation, but often symptoms are serious, the general efficacy of drug treatment is poor, usually require a heart transplant.