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目的：对比乳腺癌术后切口缝合中，一次性皮肤缝合器与可吸收缝线行连续缝合对切口愈合的影响。方法：选取32例乳腺癌改良根治术患者，随机分为两组，对照组运用可吸收缝线行连续缝合，观察组运用一次性皮肤缝合器，观测两组手术情况、切口愈合情况以及皮瓣坏死情况。结果：观察组手术时间、术中出血量、切口愈合时间、总引流量、住院时间均优于对照组；观察组甲级愈合率为75.00%，对照组甲级愈合率为31.25%；观察组1例发生皮瓣轻度（6.25%）；对照组5例发生皮瓣坏死（31.25%）。结论：一次性皮肤缝合器可提高乳腺癌改良根治术后患者切口愈合效果，减少皮瓣坏死率。“,”OBJECTIVE: to compare the postoperative incision suture of breast cancer, the disposable skin suturing device with absorbable sutures continuous suture of incision healing. METHOD: 32 cases of patients with breast cancer modified radical, randomly divided into two groups, control group using absorbable suture line continuous suture, observation group using the disposable skin suturing device, observing two groups of operation, incision healing and skin flap necrosis.RESULTS: in addition to observing group, operation time, there was no statisticaly significant difference compared with control intraoperatie blood loss, incision healing time, total flow rate, length of hospital stay were superior to control group; Group class a healing rate was 75.00%, the control class a healing rate was 31.25%; Observation group of skin flap and one mild (6.25%); Control group 5 cases of flap necrosis (31.25%).CONCLUSION: the disposable skin suturing device can improve the effect of breast cancer patients with modified radical surgery incision healing, reduce the rate of skin flap necrosis.