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目的 观察伏格列波糖对老年 2型糖尿病患者的疗效。方法 选择老年 2型糖尿病患者 ,伏格列波糖治疗组 36例 ,格列吡嗪治疗组 32例 ,治疗前、治疗 2个月后分别测定糖化血红蛋白A1C(HbA1C)、空腹及餐后 2h血糖和胰岛素。结果 2组于治疗后HbA1C、血糖均较治疗前下降 (P <0 .0 1) ,伏格列波糖组餐后 2h血糖下降幅度大于格列吡嗪组 ,空腹及餐后 2h胰岛素水平较治疗前下降 (P 均 <0 .0 5 ) ,无低血糖反应发生。结论 伏格列波糖可能成为治疗老年 2型糖尿病的有效药物之一。
Objective To observe the effect of voglibose on elderly type 2 diabetic patients. Methods A total of 36 elderly patients with type 2 diabetes, 36 patients with voglibose and 32 patients treated with glipizide were enrolled in this study. Before and 2 months after treatment, the levels of HbA1C, fasting blood glucose and 2h postprandial blood glucose And insulin. Results After treatment, HbA1C and blood glucose in both groups were significantly lower than those before treatment (P <0.01). The postprandial blood glucose levels in voglibose group at 2h were significantly lower than those in glipizide group, fasting and postprandial 2h insulin levels Before treatment decreased (P <0.05), no hypoglycemia reaction occurred. Conclusion Voglibose may be one of the effective drugs for the treatment of type 2 diabetes in the elderly.