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感染日本血吸虫尾蚴３２－３５ｄ的小鼠１次ｉｇ蒿甲醚（Ａｒｔ）３００ｍｇ·ｋｇ－１后２４ｈ，其体内♀、血吸虫的糖原含量较对照组减少约５０％，７２ｈ后则分别减少６４．１％和７７．９％。给药后７２ｈ，♀、虫的蛋白质含量较对照组分别减少６８．１％和４９．３％。给药２４ｈ，♀、虫的硷性磷酸酶（ＡＫＰ）活力的抑制率约为２５％，７２ｈ后，♀虫的ＡＫＰ进一步被抑制，抑制率达６１．６％。酸性磷酸酶（ＡＣＰ）的活力受抑制亦以♀虫较为明显，给药７２ｈ♀、虫抑制率分别为７５．７％和４７．６％。
Inoculation of Schistosoma japonicum cercaria larvae 32-35d mice once Artemether (Art) 300mg · kg-1 24h, the body of Schistosomiasis, schistosome glycogen content decreased by about 50% compared with the control group, respectively, after 72h decreased by 64 .1% and 77.9%. At 72h after administration, the protein content in gall and worm decreased by 68.1% and 49.3% respectively compared with the control group. After 24 h, the inhibitory rate of phosphoenase (AKP) activity was about 25%. After 72 h, AKP of pinworm was further inhibited and the inhibition rate reached 61.6%. The activity of acid phosphatase (ACP) was also inhibited by the pinworm, which was 75.7% and 47.6% respectively after 72h.