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目的:探讨三七总皂苷(PNS)对体内外缺血环境诱导的心肌细胞凋亡的保护作用及其可能的分子机制。方法:血清糖氧剥夺(serum glucose and oxygen deprivation,SGOD)处理72 h诱导H9c2心肌细胞凋亡作为体外心肌缺血模型,Annexin V/PI染
Objective: To investigate the protective effects of Panax Notoginseng Saponins (PNS) on cardiomyocyte apoptosis induced by ischemia in vivo and in vitro and its possible molecular mechanism. Methods: H9c2 myocardial cells were induced to apoptosis by serum glucose and oxygen deprivation (SGOD) for 72 h. As an in vitro model of myocardial ischemia, Annexin V / PI staining