呼出气作为生物样品监测,其优点是样品收集方便,非损伤性,可连续采样,受试者容易接受。同时,呼出气组份较尿、血简单,分析相对简便;而且呼出气分析可反映环境空气中化学物的时间加权平均浓度,并与血样中该物质或其代谢物的浓度相关,能反映混合静脉血浓度。挪威提出采用呼出气作为监测环己烷、苯、甲苯、二氯甲烷、三氯甲烷及四氯乙烯的最高容许值指标。但尚未被常规使用,原因之一是呼出气的采样方法的标准化存在问题。据报道,目前有三种呼气采集法,即混合呼出气(Expired Air)、终末 Breath exhalation as a biological sample monitoring, the advantage of the sample collection is convenient, non-invasive, continuous sampling, subjects are easy to accept. At the same time, the expiratory component is more urine and blood is simpler and the analysis is relatively simple; and the exhaled breath analysis can reflect the time-weighted average concentration of the chemical in the ambient air and is related to the concentration of the substance or its metabolites in the blood sample, Venous blood concentration. Norway proposed the use of expired air as a measure of the maximum allowable value for cyclohexane, benzene, toluene, methylene chloride, chloroform and tetrachlorethylene. But one of the reasons why it has not been routinely used is that there is a problem with the standardization of exhaled breath sampling methods. It is reported that there are currently three expiratory acquisition methods, namely Expired Air, terminal