目的　研究夫妇双方混苯暴露对妊娠过程和妊娠结局的影响。方法　应用回顾性队列研究方法对某石化企业女工的妊娠过程向妊娠结局进行了发析。结果　孕期浮肿、孕期贫血、自然流产和出生缺陷的发生率以双方暴露组最高 ,而双方皆不接触组最低 ,有显著性差异 (P <0 0 5 )。结论　丈夫也接触混苯可加重妊娠并发症及不良妊娠结局的发生 Objective To study the effect of mixed benzene exposure on the course of pregnancy and pregnancy outcome. Methods A retrospective cohort study was conducted to analyze the pregnancy outcome of female workers in a petrochemical enterprise. Results The incidence of edema during pregnancy, anemia during pregnancy, spontaneous abortion and birth defects were the highest in both groups and the lowest in both groups (P <0.05). Conclusion Husband also contact with benzene can aggravate pregnancy complications and adverse pregnancy outcomes