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亚硝胺类化合物致癌问题已受到普遍重视。本文表明:浅表性胃炎患者胃液亚硝酸盐含量为0.0110±0.0057mg-N/dl。胃癌患者胃液亚硝酸盐含量为0.0298±0.0243mg-N/dl,显著高于浅表性胃炎患者(P<0.002)。萎缩性胃炎患者胃液亚硝酸盐含量为0.0218±0.0220mg-N/dl,亦明显高于浅表性胃炎患者(P<0.05)。提示胃癌发病与胃液内亚硝酸盐含量增高密切相关。
The carcinogenicity of nitrosamines has received widespread attention. This article shows that the content of nitrite in gastric juice in patients with superficial gastritis is 0.0110±0.0057 mg-N/dl. The content of nitrite in gastric juice was 0.0298±0.0243 mg-N/dl, which was significantly higher than that in patients with superficial gastritis (P<0.002). The content of nitrite in gastric juice in patients with atrophic gastritis was 0.0218±0.0220 mg-N/dl, which was also significantly higher than that in patients with superficial gastritis (P<0.05). It is suggested that the onset of gastric cancer is closely related to the increase of nitrite content in gastric juice.