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目的比较阿替卡因肾上腺素注射液(必兰)和利多卡因在宫颈LEEP手术中的麻醉镇痛效果,探讨必兰用于宫颈LEEP手术麻醉的可行性及安全性。方法选取2007年7月-2009年12月该院门诊240例需行LEEP术的CIN患者,随机分为必兰组、利多卡因组及对照组,每组各80例患者,必兰组术前2 min宫颈注射必兰1.7 ml,利多卡因组术前2 min宫颈注射2%利多卡因5 ml,对照组术前不用任何麻醉药物。结果必兰组与利多卡因组及对照组比,术中、术后出血量明显减少、镇痛效果更好,伤口愈合快,差异有统计学意义(P<0.05);利多卡因组与对照组相比,术中疼痛减轻,但出血量、术后伤口愈合率差异无统计学意义(P>0.05)。结论必兰能为LEEP术患者提供更好的术中镇痛效果,同时减少出血,不良反应少,安全性更高。
Objective To compare the analgesic effect of artecine epinephrine injection (BLL) and lidocaine in cervical LEEP operation and to discuss the feasibility and safety of Bilan anesthesia in cervical LEEP operation. Methods From July 2007 to December 2009, 240 patients with CIN who underwent LEEP in our clinic were randomly divided into two groups: Bilan group, lidocaine group and control group, with 80 patients in each group. Bilan group Before the first 2 min cervical injection of 1.7 ml, lidocaine 2 min before the injection of 2% lidocaine cervical 2, the control group without preoperative anesthesia. Results Compared with the lidocaine group and the control group, the bleeding volume and the postoperative bleeding in the group B and C were significantly decreased, the analgesic effect was better and the wound healing was faster, the difference was statistically significant (P <0.05) Compared with the control group, intraoperative pain relief, but the amount of bleeding, postoperative wound healing rate difference was not statistically significant (P> 0.05). Conclusions Biolan can provide better intraoperative analgesia for LEEP patients with less bleeding, less adverse reactions and higher safety.