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目的:为有效改善患者溃疡症状,提高患者生活质量,研究分析使用雷贝拉唑三联疗法治疗由幽门螺杆菌引发的十二指肠溃疡的效果。方法:选取我院2014年3月至2015年4月期间90例十二指肠溃疡患者,按入院时间分为雷贝组和西咪组,每组45例,雷贝组采用雷贝拉唑三联疗法治疗溃疡,西咪组采用西咪替丁三联疗法治疗,观察两组疗效以及服药后发生不良反应的情况。结果:服药1 w后两组治疗总有效率相比,雷贝组高达91.1%,西咪组只有75.6%,雷贝组较西咪组疗效好(P<0.05);服药后雷贝组不良反应发生率为15.6%;西咪组发生率高达33.3%,西咪组较雷贝组不良反应多(P<0.05)。结论:因幽门螺杆菌感染引发的十二指肠溃疡患者采用雷贝拉唑三联疗法,病患疗效好,服药后不良反应少,可临床推广应用。
Objective: In order to effectively improve the symptoms of patients with ulcers and improve the quality of life of patients, the study analyzed the effect of using rabeprazole triple therapy in the treatment of H. pylori-induced duodenal ulcer. Methods: A total of 90 patients with duodenal ulcer between March 2014 and April 2015 in our hospital were enrolled in this study. According to the time of admission, they were divided into rebebe and cimetidine group, 45 cases in each group. Rabeprazole Triple therapy for ulcer, cimi group cimetidine triple therapy, the two groups observed the efficacy and adverse reactions after taking the case. Results: After 1 w of treatment, the total effective rate of the two groups was 91.1% in the Rebbe group and 75.6% in the Sifei group, and was better in the Rebebei group than in the Simei group (P <0.05) The incidence of the reaction was 15.6%. The incidence of cimetidine was as high as 33.3%. More adverse reactions were observed in the radix cimetidine group than in the radix phellodendron group (P <0.05). Conclusions: Rabeprazole triple therapy is used in patients with duodenal ulcer caused by Helicobacter pylori infection. The patients have good curative effect and few side effects after taking medicine. They can be used clinically.