使用共沉淀法利用含有氨基的壳聚糖、含有羧基的柠檬酸钠调控合成了原位包覆的Fe3O4纳米颗粒,并研究了氨基与羧基在调控合成Fe3O4纳米颗粒方面的规律及机理。通过改变氨基、羧基的用量可实现不同尺寸Fe3O4纳米颗粒的可控合成。此外氨基与羧基的共同调控可合成粒度约10nm的Fe3O4纳米颗粒。 Co-precipitation method using amino-containing chitosan, sodium citrate containing carboxyl-mediated synthesis of in situ coated Fe3O4 nanoparticles, and amino and carboxyl in regulating the synthesis of Fe3O4 nanoparticles in the law and mechanism. Controllable synthesis of Fe3O4 nanoparticles with different sizes can be achieved by changing the amount of amino groups and carboxyl groups. In addition, the common regulation of amino groups and carboxyl groups can synthesize Fe3O4 nanoparticles with particle size of about 10nm.