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目的研究血清肌酸激酶同工酶(CK-MB)与心肌肌钙蛋白Ⅰ(cTnI)检测在病毒性心肌炎患儿诊断中的价值。方法将39例病毒性心肌炎患儿作为观察组,以同期行常规体检的39例健康儿童作为对照组,对比两组的cTnI、CK-MB的检测结果,并在观察组内对比cTnI与CK-MB的阳性率。结果观察组患儿发病1～2d时cTnI与CK-MB与对照组均有显著差异;发病7d及14d时观察组cTnI与对照组有显著差异。观察组内患儿发病1～2d时cTnI检测阳性率明显高于CK-MB;7d与14d时cTnI检测的阳性率则显著高于CK-MB。结论 cTnI在病毒性心肌炎的诊断中均具有较高的特异度与敏感度。
Objective To investigate the value of serum creatine kinase (CK-MB) and cardiac troponin I (cTnI) in the diagnosis of children with viral myocarditis. Methods Thirty-nine children with viral myocarditis were enrolled in this study. 39 healthy children who underwent regular physical examinations during the same period were taken as control group. The results of cTnI and CK-MB were compared between two groups. The levels of cTnI and CK- MB positive rate. Results The incidence of cTnI and CK-MB in the observation group was significantly different from that in the control group on the 1st and 2nd day after the onset of the disease. At 7 and 14 days, the cTnI in the observation group was significantly different from that of the control group. The positive rate of cTnI in the observation group was significantly higher than that in CK-MB at 1 ~ 2d after onset of disease. The positive rate of cTnI in observation group was significantly higher than that of CK-MB at 7d and 14d. Conclusion cTnI has high specificity and sensitivity in the diagnosis of viral myocarditis.