本实验利用中国小型猪制作动脉粥样狭窄病变模型。采用球囊扩张的方法对15头小型猪骼动脉内膜进行损伤并饲以高脂饮食，术后12周病理检查内膜增生及管腔狭窄情况。结果显示：13头动物26支血管有门支（46．2％）狭窄程度超过50％，其中4支（15．4％）血管完全闭塞。表明中国小型猪不仅能诱发动脉粥样硬化病变，而且在血管损伤的基础上也可以产生动脉病变。 This experiment made use of Chinese miniature pig atherosclerosis lesion model. Fifteen small pig skeletal artery intima were injured by balloon dilation and fed with a high-fat diet. Pathological examination of neointimal hyperplasia and stenosis was performed 12 weeks after operation. The results showed that there were more than 50% stenosis of 26 vessels in 13 animals (46.2%), of which 4 vessels (15.4%) were completely occluded. This shows that Chinese miniature pigs can not only induce atherosclerotic lesions, but also produce arterial lesions on the basis of vascular injury.