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目的 :探讨儿童和成人紫癜性肾炎 ( HSPN)的差异。方法 :对 6 1例儿童及 10 4例成人 HSPN的临床表现、病理改变及预后进行分析和比较。 结果 :1儿童表现为高血压、肾功能不全及少尿者的比例低于成人 ;2儿童的病理分级为 ~ 级者的比例低于成人 ;3随访中儿童完全缓解及改善的比例高于成人 ,而恶化的比例低于成人。 结论 :总体上 ,儿童 HSPN无论是临床表现还是病理改变均较成人轻 ,故预后较成人好
Objective: To explore the difference between children and adult purpura nephritis (HSPN). Methods: The clinical manifestations, pathological changes and prognosis of HSPN in 61 children and 10 4 adults were analyzed and compared. Results: 1 The prevalence of hypertension, renal dysfunction and oliguria in children was lower than that in adults; the rate of pathological grade of 2 children was lower than that of adults; 3 The rate of complete remission and improvement was higher in children than in adults , While the rate of deterioration is lower than that of adults. Conclusion: Overall, the prognosis of children HSPN is better than that of adults, both in clinical manifestations and pathological changes