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目的研究银杏达莫注射液联合阿斯匹林治疗短暂性脑缺血发作(TIA)的临床疗效。方法72例频发TIA患者,随机分为2组:治疗组36例应用银杏达莫注射液20ml静脉滴注,阿斯匹林25mg,每日1次口服;对照组36例采用丹参注射液20ml静脉滴注,同时口服阿斯匹林100mg,每日1次。观察2组临床疗效及血液流变学指标。结果治疗组患者临床速控率明显优于对照组(77.8%vs25.0%,P<0.05);治疗组纤维蛋白原水平治疗后较治疗前明显降低〔(2.22±0.40)g/Lvs(5.04±0.66)g/L,P<0.05)〕,且低于对照组治疗后水平〔(2.22±0.40)g/Lvs(4.76±0.55)g/L,P<0.05〕;其他血液流变学指标治疗组治疗后也低于治疗前,且低于对照组治疗后。结论银杏达莫注射液联合阿斯匹林治疗频发TIA有显著疗效。
Objective To study the clinical efficacy of Yinxingdamo injection combined with aspirin in the treatment of transient ischemic attack (TIA). Methods Seventy-two patients with TIA were randomly divided into two groups: 36 cases in the treatment group were treated with 20 ml intravenous injection of gingko Damo injection and 25 mg aspirin once daily. In the control group, 36 cases were treated with 20 ml Salvia miltiorrhiza injection Intravenous infusion, while oral aspirin 100mg, 1 day. The clinical curative effect and hemorheology indexes of 2 groups were observed. Results The rate of clinical control in treatment group was significantly better than that in control group (77.8% vs 25.0%, P <0.05). The fibrinogen level in treatment group was significantly lower than that before treatment [(2.22 ± 0.40) g / L vs ± 0.66) g / L, P <0.05), and lower than that of the control group [(2.22 ± 0.40) g / L vs (4.76 ± 0.55) g / L, P < The treatment group after treatment was also lower than before treatment, and lower than the control group after treatment. Conclusion Yinxingdamo injection combined with aspirin in the treatment of frequent TIA have a significant effect.