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目的探讨急性期血压对脑梗死患者认知功能的影响。方法选取2013年4月到2015年4月于北京市垂杨柳医院接受治疗的发病24 h内入院的脑梗死患者132例,按照住院后前3 d平均收缩压水平将其分为A组30例、B组61例、C组41例,其中A组平均收缩压90~130 mm Hg,B组130~160 mm Hg,C组大于160 mm Hg,三组患者分别在入院24 h、入院15 d、病后6个月采用美国国立卫生院神经功能缺损评分(NIHSS量表)、蒙特利尔认知评估(MoCA)量表对患者神经、认知功能进行评价,比较三组患者在神经功能缺失程度和认知功能上的差距。结果三组患者入院24 h、入院15 d、发病6个月认知功能评分、神经功能评分比较差异有统计学意义;A、C组入院24 h、入院15d、发病6个月认知功能评分低于B组,神经功能评分高于B组,差异均有统计学意义(P<0.05)。结论处于一定血压区间对脑梗死患者认知功能有保护作用。
Objective To investigate the effect of acute phase blood pressure on cognitive function in patients with cerebral infarction. Methods Thirty-two patients with cerebral infarction who were hospitalized within 24 hours from April 2013 to April 2015 in Beijing Chuanyangliu Hospital were divided into three groups according to the average systolic blood pressure level of the first 3 days after hospitalization: group A , 61 in group B and 41 in group C. The average systolic blood pressure was 90-130 mm Hg in group A, 130-160 mm Hg in group B, and 160 mm Hg in group C. The patients in three groups were admitted to hospital for 24 h, Six months after the illness, neurological deficit score (NIHSS scale) and Montreal Cognitive Assessment (MoCA) scale of the National Institutes of Health were used to evaluate the neurological and cognitive functions of the patients in the three groups. Cognitive function of the gap. Results There was significant difference in cognitive function scores and neurological function scores between the three groups of patients admitted to hospital for 24 h and admission for 15 days and 6 months after onset of hospitalization. Patients in groups A and C were admitted to hospital for 24 hours and admitted to hospital for 15 days, Lower than group B, neurological score was higher than group B, the difference was statistically significant (P <0.05). Conclusion A certain range of blood pressure has a protective effect on cognitive function in patients with cerebral infarction.